EUS Guided Tissue Acquisition

Endoscopic ultrasound-guided tissue acquisition (EUS-TA) is a minimally invasive technique used to obtain tissue samples from deep-seated lesions for diagnostic and therapeutic purposes. It is performed using fine-needle aspiration (FNA) or fine-needle biopsy (FNB), providing a high level of accuracy in evaluating pancreatic, gastrointestinal, mediastinal, and other abdominal lesions.

Procedure

EUS-TA combines the imaging capabilities of EUS with needle-guided sampling. The procedure involves:

• Localizing the target lesion using high-resolution ultrasound.
• Advancing a fine needle (FNA or FNB) through the endoscope into the lesion.
• Aspiration or coring of tissue for cytological or histological evaluation.

FNA: Primarily used to aspirate fluid or cellular material for cytological analysis.

FNB: Uses specialized needles to obtain core tissue samples for histopathological evaluation.

Advantages

• High diagnostic accuracy (up to 90% for malignancies).
• Minimally invasive, reducing the need for surgical biopsies.
• Real-time imaging ensures precise needle placement.