Dr Shamsher Singh Chauhan

Fatty Liver

Fatty liver disease is a condition where excess fat accumulates in liver cells. It is a reversible condition in its early stages, but if left unmanaged, it can progress to more severe liver damage, including cirrhosis.

Types of Fatty Liver

  • Non-Alcoholic Fatty Liver Disease (NAFLD): Fat buildup not related to alcohol consumption.
  • Alcoholic Fatty Liver Disease (AFLD): Fat accumulation due to excessive alcohol intake.

Symptoms

Fatty liver disease often presents with no symptoms in the early stages. However, as the condition progresses, individuals may experience:

  • Fatigue and weakness.
  • Discomfort or pain in the upper right abdomen.
  • Unexplained weight loss.
  • Enlarged liver (hepatomegaly).
  • Jaundice (in advanced stages, indicating liver dysfunction).

Causes

The primary causes and risk factors for fatty liver include:

NAFLD:

  • Obesity.
  • Insulin resistance and type 2 diabetes.
  • High cholesterol or triglyceride levels.
  • Sedentary lifestyle and poor dietary habits.
  • Genetic predisposition.

AFLD:

  • Chronic alcohol consumption.
  • Malnutrition or binge drinking.

Diagnosis

  • Blood tests showing elevated liver enzymes.
  • Imaging studies like ultrasound, CT scan, or MRI.
  • Liver biopsy for definitive diagnosis and staging.

Treatment

Management focuses on addressing the underlying causes and preventing progression:

Lifestyle Modifications:

  • Weight loss: Gradual reduction of 7-10% of body weight can improve liver health.
  • Dietary changes: Adopt a balanced diet rich in fruits, vegetables, whole grains, and lean proteins. Limit saturated fats, sugar, and processed foods.
  • Exercise: Engage in at least 150 minutes of moderate aerobic exercise per week.

Alcohol Abstinence: Crucial for AFLD patients.

Medications:

  • No FDA-approved medication for fatty liver exists, but treatments may include drugs to manage diabetes, cholesterol, or insulin resistance.
  • Vitamin E and certain anti-inflammatory medications may help NAFLD in specific cases.
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